What am I learning about my Microbiome?

In recent years we have studied the intestinal microbiome of 200 healthy individuals from 4 large cities in Argentina, which allowed us to assemble our own database that constitutes our local reference microbiome.

 

Your gut microbiome is going to be compared against this database. This comparison allows us to identify the characteristics of your microbiome with respect to the reference individuals. These data, together with the information on your habits and lifestyle, will allow us to generate recommendations and a personalized nutrition and habits plan to improve your general well-being.

 

Below you will learn what type of information of your microbiome will be in the analysis.

The composition of your gut microbiome is dynamic and is largely influenced by dietary habits and lifestyle. Using artificial intelligence techniques on our database of reference individuals, we group them into 3 different enterotypes, according to the community of bacteria that predominates in the gut of each one of them. Therefore, in the Argentine population we find the following enterotypes:

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Enterotype 1, dominated by Firmicutes, especially Ruminoccoccus, is typical in rural populations or living far from large urban settlements with a balanced diet based on fiber-source foods such as whole cereal grains, which have low complex carbohydrates. digestibility. This fiber is degraded by these microorganisms and transformed into butyrate, a molecule with beneficial and anti-inflammatory properties for the human body. Just because you live in a city doesn't mean you can't have this healthy enterotype. To a large extent it depends on your diet and habits.

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Enterotype 2, dominated by Bacteroides is typical in megacities and westernized / industrialized urbes. It is associated with a diet with a high percentage of foods rich in animal proteins and fats and low in fiber. It is perhaps the least healthy enterotype and most associated with various metabolic problems, propensity for colon cancer and other chronic health conditions.

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The enterotype 3 dominated by Prevotella is typical in diets rich in fruits and vegetables, which are a very good source of fiber, which in turn leads to produce butyrate and other molecules beneficial to health. But this enterotype also makes good use of refined carbohydrates (sugar, sweets, the like) that are dangerous to health. Anyway, in general terms, it would indicate a healthier lifestyle than 2.

Current microbiome type

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There are a number of key indices that will help us get an overview of the overall health of your gut microbiome.

  • Diversity, richness and Balance

  • Integrity

 

Diversity is one of the most important measures of the microbiome, it characterizes the balance or balance of the community of microbes that inhabit the intestine. Good diversity indicates a healthy microbiome, and in general the more biodiverse the better, as this indicates that there are different bacteria providing useful functions for the proper functioning of the body.

The report of your microbiome contains a very simple graph to understand how the diversity of your microbiome is compared to the reference individuals.

 

Diversity is affected by 2 key components which are the richness and Balance of the species that compose it.

We invite you to learn more about these indices and the relationship between them in this blog post READ MORE

 

If you took antibiotics in the last year or some type of chronic medication that may be affecting your microbiome, you will be interested in observing the Integrity index

 

If you want to know more about microbial diversity and what you can do to improve it, we invite you to read our blog. READ MORE

General Microbiome Health

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The F / B (Firmicutes / Bacteroidetes) index is another of the basic measures of the microbiome health. Balance is the key word in this case to be healthy, neither too high nor too low are beneficial to your health in the medium-long term

A high F / B index is observed in people with a tendency to obesity, diabetes, fatty liver, biomarkers of inflammation, among other disorders of metabolic homeostasis. A high F / B ratio means that your Firmicutes far exceed your Bacteroidetes (Bacteroides / Prevotella). A situation that a priori is not good.

 

A very low F / B index means that your Bacteroidetes far exceed your Firmicutes, if this is also associated with an enterotype 2 (Bacteroides) it can lead to inflammatory processes that culminate in a high probability of colon cancer due to a shortage of key molecules with anti-inflammatory properties such as butyrate.

 

There are many actions that can be taken to improve this index ranging from changing habits to lifestyle. On the other hand, if no action is taken it could lead to chronic health risks in the long term.

 

Find out how the F / B ratio is in your gut microbiome and what you can do to improve it. READ MORE

 

 

Risk of metabolic diseases

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The composition of your microbiome is UNIQUE and DYNAMIC , no two are exactly alike, not even if you have a twin brother! On the other hand, there are patterns that resemble each other and allow us to compare to obtain important conclusions about your habits and your health.

Phylum is the highest category of bacteria classification that we will find in your gut microbiome. Typically there are about 6 different types, where Firmicutes and Bacteriodetes predominate, but a high level of Proteobacteria can be present which could indicate some additional problem such as chronic diseases.

 

Families is an intermediate category of bacteria classification that we will find in your microbiome. It is typically disaggregated into 20 categories that come from the 6 found Filos and provide us with more detailed information about the health of your microbiome

 

READ MORE

Composition of the microbiome

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Over the last few years, much scientific evidence has been collected suggesting that imbalances in the proportions of bacteria in the gut have a correlation with the appearance of symptoms, or health conditions. We have prepared a selection of reports associated with certain conditions such as:

  • Abdominal pain

  • Swelling

  • Constipation

  • Damage to the intestinal mucosa (Leaky gut)

Intestinal Health

New Categories

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We are developing new categories to boost your gut microbiome and healthy habits . Soon you will be able to check how your microbes can boost the following categories :

  • Nutrition

  • Physical exercise

  • Immunity

  • Sleep Efficiency

 

Computadoras

Can I see a demo of the microbiome results?

Of course you can, you can click the button below and download a model image of what the microbiome results look like. When you participate in the program you will get a more complete downloadable report.

Do they have scientific support for the results?

Of course you can, you can read the scientific validation work that we have developed over several years in Héritas on the human microbiome. Of course, since they are scientific papers, a certain level of specialized knowledge is required to read them, if you are linked to science and technology, or you are curious, we invite you to read them.

 

You can also see this video (40 min) of a webinar that our scientific director gave explaining the work done.

 

Validation paper 2