Sample ID

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Current Microbiome Type

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ENTEROTYPE

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DC

RC

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What are enterotypes?

The type of microbiome, called an enterotype , is largely influenced by long-term dietary habits. In the Argentine population we find the following enterotypes:

  Enterotype 1

Most bacteria adapted to diets rich in complex carbohydrates, such as dietary fiber from grains, and resistant starches such as those contained in potatoes and lentils. The type of diet commonly found in agricultural populations.

Enterotype 2

Most adapted bacteria adapted to western diets high in protein and animal fats. This is the majority enterotype of our population

Enterotype 3

Most adapted bacteria adapted to diets with high fiber content of foods such as vegetables, fruits; and refined carbohydrates such as pastry products.  

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General Microbiome Health

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RD

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Diversity index

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Wealth index

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Balance index

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Integrity index

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What does microbial diversity mean?

Diversity is one of the most important measures of the microbiome, it characterizes the balance or balance of the community of microbes that inhabit the intestine. Good diversity indicates a healthy microbiome, and in general the more biodiverse the better, as this indicates that there are different bacteria providing useful functions for the proper functioning of the body.

Why are microbial richness and balance important for diversity?

A good diversity is made up of 2 indices that are the richness and balance of the bacteria present in the intestine. If something is not right with your diversity it is important that we observe these 2 indices.
The richness index describes the number of different types of bacteria present in the intestine. The balance indicates how the proportions of these different bacteria are distributed.
A greater number of different bacteria, which increase microbial diversity, can contribute to different functions necessary for humans. As a result, the body can better use food and nutrients, and function better overall. A low balance index may be indicating that one or more types of bacteria in particular are dominating your intestinal microbiome in abundance, and this is usually not good since it affects diversity, even when your wealth
(total number of different bacteria) is high. In a good diversity, there are no types of bacteria that are very dominant in abundance over the rest. In the same way, having a good balance between them when wealth is very low also undermines good diversity. A diverse microbiome is the best prepared to face the day to day in our lives.

What does the integrity index measure?

It is known that the bacteria that belong taxonomically to the Bacteroidia and Clostridria classes defend us better against the invasion or colonization of pathogens, and on the other hand, the Gammaproteobacteria and the Bacilli are more associated with favoring imbalances.

The integrity index looks at the ratio of abundance between all these bacteria to give us an estimate of how well prepared we are to face infections. It is known that taking antibiotics or certain chronic medications affect this integrity index to a greater or lesser extent. That is why it is important that we check if your integrity index is favorable or if we should improve it, especially if you have been exposed to antibiotics lately or to chronic medications.

 
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Risk of metabolic diseases

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RD

Firmicutes / Bacteroidetes Index

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Diversity description

What does the Firmicutes / Bacteroidetes relationship mean?

A high F / B index is observed in people with a tendency to obesity, diabetes, fatty liver, biomarkers of inflammation, among other disorders of metabolic homeostasis. A high F / B means that your Firmicutes far exceed your Bacteroidetes (Bacteroides / Prevotella). This is not good.

A very low F / B index means that your Bacteroidetes far exceed your Firmicutes, if this is also associated with an enterotype 2 (Bacteroides) it can lead to inflammatory processes that culminate in a high probability of colon cancer due to a shortage of anti molecules. -Key inflammatory drugs such as butyrate.

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Composition of the microbiome
Edge Level

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How to interpret the graphics?

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DF

Family Level

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DF

 

How is the microbiome organized?

The intestinal microbiome is a complex interaction of diverse microorganisms, among them bacteria, viruses and fungi, the overwhelming majority being bacteria of different types.

To organize ourselves and understand well the complexity of bacteria in the microbiome, they are organized taxonomically, that is, into different categories. Taxonomy is a principle used in biology to carry out an organized and hierarchical classification of the different types present in a sample.

So, we have introduced two key concepts: 1) Organized, 2) Hierarchical.

Taxonomy organizes the bacteria of the microbiome from a broader concept to a more specific concept in a nested form of categories. These categories are given in the following order (from least specific to most specific):

Domain ---> Kingdom ---> Phylum (Phylum) ---> Class ---> Order ---> Family ---> Genus ---> Species.

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Intestinal health

Consider:

This section reports on microorganisms that, according to the scientific literature, predispose to the appearance ("associated"), or protect ("protective") certain symptoms or frequent manifestations of intestinal health. It is very important to understand that the report of microorganisms associated with a certain intestinal health situation indicates PREDISPOSITION that may or may not manifest itself and to a greater or lesser extent, depending on other concomitant circumstances in habits.

In conclusion, this information does not represent a diagnosis but rather a screening that indicates predisposition.

Predisposition to abdominal pain:

Beef

Associates

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Protective

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Predisposition to swelling:

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Associates

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Protective

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Predisposition to constipation:

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Associates

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Protective

B

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Predisposition to damage to the intestinal mucosa:

Beef

Associates

B

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Protective

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